/******************************************************************************/
/************************* Bootstrap Customizations ***************************/
/******************************************************************************/
a,
a:hover,
a:visited,
a:focus{
  text-decoration: none; }

a {
  color: #0088CC; }

a:hover {
  color: #cb521e;
  cursor: pointer;
}

img {
  width: auto; }

a img {
  vertical-align: middle; }

body {
  font-family: Arial, Verdana, sans-serif;
  line-height: 1.428571429;
  color: #505050;
  background-color: #fff; }

  
.glyphicon-large{
  font-size: large;
}

.btn:focus,
.btn.active:focus,
.btn.active.focus,
.btn-default:focus{
  outline: none;
  outline-offset: 0;
}

.btn.active{
  box-shadow: none;
}

.button-hover:hover{
  color: #333;
  background-color: #e6e6e6;
  border-color: #adadad;
}

.button-normal{
  color: #333;
  background-color: #FFF;
  border-color: #CCC;
}

.row{
  margin: 0px;
}

table.main-table {
  margin-bottom: 0px;
}

table.table.main-table th,
table.table.main-table td{
  border-right: 1px solid darkgray;
  border-left: 1px solid darkgray;
  text-align: left;
}

table.table.main-table th{
  font-size: 11pt;
  color: #5C5C5C;
  background-color: lightgrey;
  border-top: 1px solid darkgray;
  border-bottom: 1px solid darkgray;
  padding: 10px;
  text-align: justify;
  vertical-align: top;
}

table.table.main-table td{
  padding: 4px 8px 0 8px;
  border-bottom: 1px solid lightgray;
  line-height: 1.5em;
}

table.table.main-table tr:nth-child(even) {
  background-color: #f1f1f1;
}

table.table.main-table td{
  padding: 4px 8px 0 8px;
}

table tbody{
  color: #5C5C5C;
}

.table-fixed {
  position: -webkit-sticky;
  position: -moz-sticky;
  position: -ms-sticky;
  position: -o-sticky;
  position: sticky;
  top: 0;
  z-index: 10;
  width: 100%;
}

.table-header{
  position: -webkit-sticky;
  position: -moz-sticky;
  position: -ms-sticky;
  position: -o-sticky;
  position: sticky;
  top: 0;
  z-index: 10;
}

.dropdown-menu > .active > a,
.dropdown-menu > .active > a:hover,
.dropdown-menu > .active > a:focus {
  color: black;
  font-weight: bold;
  text-decoration: none;
  background-color: #E1E2E2;
  outline: 0;
}
/******************************************************************************/
/************************* End Bootstrap Customizations ***********************/
/******************************************************************************/

#app-container {
  max-width: 1280px;
  min-width: 980px;
  padding: 0;
}

.neb-blue{
  color: #022e4f;
}

.neb-orange{
  color: #F58025;
}

.neb-red{
  color: #cf324e;
}

.neb-dark-blue{
  color: #659fcf;
}

.nebheader {
  background-image: url("../images/bg-grey-texture-low.jpg");
}

.neb-textbox{
  width: 50px;
  height: 26px;
  text-align: center;
  line-height: 1em;
  border: 1px solid darkgrey;
}

/******** NEB Dropdown CSS ********/
.neb-dropdown{
  height: 25px;
  color: #404040;
  line-height: 1em;
  border: 1px solid #b3b3b3;
  padding: 1px 1px 0px 1px;
  background-color: #e6e6e6;
  border-radius: 2px;
}

.neb-dropdown::-ms-expand {
  display: none;
}

.neb-dropdown:focus{
  outline: none;
}

.neb-dropdown:focus::-ms-value {
  background: none;
  color: black;
}

.neb-dropdown option{
  background-color: white;
}

.neb-dropdown:hover{
  background-color: #d4d4d4;
}

@-moz-document url-prefix() {
  .neb-dropdown,
  .neb-dropdown option{
    padding-left: 15px;
    padding-right:10px;
  }
}
/******** End NEB Dropdown CSS ********/

*[data-toggle="modal"]{
  cursor: pointer;
}

#main-page-title {
  display: inline-block;
  flex: 1 1 auto;
  margin-bottom: 0;
}

#imgHeader {
  display: inline-block;
  flex: 0 0 20%;
  margin: 0 0 5px 0;
}

.header-container{
  margin-bottom: 20px;
}

#help-back-btn{
  margin-left: 15px;
}

#help-description{
  font-size: 16px;
}

.help-description{
  font-size: 16px;
}

#close-btn{
  padding-left: 0px;
  padding-top: 15px;
  padding-right: 5px;
  padding-bottom: 0px;
}

#help-modal-header{
  padding-left: 25px;
  padding-top: 0px;
  padding-right: 25px;
  padding-bottom: 0px;
}

#help-modal-body{
  padding-left: 25px;
  padding-top: 5px;
  padding-right: 25px;
  padding-bottom: 0px;
}

#help-footer-modal{
  padding-left: 25px;
  padding-top: 15px;
  padding-right: 20px;
  padding-bottom: 15px;
}

#help-footer-btn{
  padding-left: 0px;
}

.backtoneb {
  display: block;
  position: absolute;
  top: 10px;
  right: 0;
  z-index: 1;
  min-height: 30px;
  font-size: 0.8em;
  text-align: center;
  color: #ffffff;
  padding: 10px 20px 0 0; }

.nebheaderlogo {
  display: block;
  float: left;
  margin: 10px 0 0 20px;
  width: auto;
  height: 60px;
  overflow: hidden; }

.toolheader {
  align-items: flex-end;
  border-style: solid;
  border-width: 0 0 4px 0;
  border-color: #022e4f;
  display: flex;
  justify-content: space-between;
  padding: 10px 0;
}

.toolheadername {
  display: none;
  flex: 0 0 20%;
  margin: 0;
  padding-left: 20px;
}

.toolheaderlogo {
  margin: 0;
  padding-left: 20px;
  width: auto;
  height: auto;
  overflow: hidden;
}

.toolheader-link-container {
  display: inline-block;
  flex: 0 1 auto;
  padding-right: 20px;
}

.toolheader-link {
  float: right;
  margin-left: 10px;
  color: #626366; }

.toolfooter {
  align-items: flex-end;
  background-color: #ed6823;
  background-image: url("../images/bg-footer-nav-low.jpg");
  background-position: center center;
  background-repeat: no-repeat;
  display: flex;
  justify-content: space-between;
}

.toolfooterlogo {
  height: auto;
  margin: 10px 0 0 20px;
  overflow: hidden;
  width: auto;
}

.toolfooter-link {
  color: #ffffff;
  font: 1em/1.38 Arial;
  padding: 0.5em;
  text-align: center;
}

.nebfooter {
  background-color: #3a3a3a;
  background-image: url("../images/bg-grey-texture-low.jpg");
  background-position: center center;
  background-repeat: no-repeat;
  padding-bottom: 15px;
}

.nebfooterlinkcontainer {
  margin: 0 auto;
  width: 450px;
  height: 100%;
}

.nebfooterlink {
  display: inline-block;
  font-size: 0.8em;
  text-align: center;
  color: #ffffff;
  margin-top: 15px;
  margin-left: 5%;
}

.nebfooterlink img {
  margin-right: 10px;
}

.nebfooterlink:link,
.nebheader a:link,
.toolfooter a:link {
  color: white;
}

.nebfooterlink:visited,
.nebheader a:visited,
.toolfooter a:visited {
  color: white;
}

.toolfooter a:hover {
  color: #cb521e;
}

.nebfooterlink:active,
.nebheader a:active,
.toolfooter a:active {
  color: white;
}

.nebfooterlink:hover,
.nebheader a:hover{
  color: #cb521e;
}

.toolheader a:link {
  color: #626366; }

.toolheader a:visited {
  color: #626366; }

.toolheader a:active {
  color: #626366; }

.toolheader a:hover {
  color: #cb521e; }

#sidebar-subheading {
  margin-top: 10px;
  left: 0;
  font-size: 1em;
  font-weight: bold;
  overflow: hidden;
}

input[type="radio"], input[type="checkbox"] {
  display: inline-block;
  opacity: 0; }

input[type="radio"] + label,
input[type="checkbox"] + label {
  display: inline-block; }

input[type="radio"] + label:before,
input[type="checkbox"] + label:before {
  content: "";
  display: inline-block;
  width: 18px;
  height: 18px;
  margin: 1px 4px 5px -18px;
  vertical-align: middle;
  background: url(../images/check_radio_sheet.png) left top no-repeat; }

input[type="radio"]:checked + label:before {
  background: url(../images/check_radio_sheet.png) -36px top no-repeat; }

input[type="checkbox"]:checked + label:before {
  background: url(../images/check_radio_sheet.png) -18px top no-repeat; }

.radio-list input[type=radio] + label {
  font-weight: normal;
}

.checkbox-with-label {
  display: inline-block;
  padding: 0 0;
  font-weight: normal;
  margin-right: 10px;
  position: relative;
}

.checkbox-with-label label {
  font-weight: normal; }

.input-group-addon {
  background: white;
}

.input-group-btn + input[type=text] {
  border-left: none;
}

.input-group-btn > .btn {
  background-color: #eee;
  border-color: gray;
  color: #5C5C5C;
  font-weight: bold;
  width: 100%;
}

#sequence-text {
  width: 100%;
  min-height: 100px;
  max-height: 300px;
  max-width: 414px;
  resize: vertical;
}

.project-btn {
  text-overflow: ellipsis;
  width: 96%;
  height: 37px;
  display: inline-flex;
}

hr {
  margin: 0 50px 0 50px;
}

.question-icon {
  font-size: medium;
  cursor: pointer;
  color: #022e4f;
  padding-left: 0px;
}

.warning-icon {
  font-size: medium;
  cursor: pointer;
  color: #ebc015;
  padding-left: 0px;
}

.modal-question-icon,
.modal-question-icon:focus,
.modal-question-icon:active,
.modal-question-icon:active:visited {
  color: #515151;
  cursor: pointer;
  font-size: medium;
  padding-left: 10px;
  text-decoration: none;
}

.tt-dataset-plasmids,
.tt-dataset-virals {
  max-height: 200px;
  overflow-y: auto;
  width: 100%;
}

#plasmid-input, #viral-input {
  display: inline-flex;
  width: 94%;
  max-width: 415px;
}

#plasmid-input .twitter-typeahead {
  width: 100%;
  white-space: nowrap;
}

.typeahead-caret {
  height: 33px;
  margin: 0 0 0 2px;
}

#viral-input .twitter-typeahead {
  width: 100%;
  white-space: nowrap;
}

#gencode-input {
  width: 100%;
  text-align: left;
}

.twitter-typeahead .tt-hint {
  margin-bottom: 0;
}
.tt-hint {
  color: #999;
}

.tt-menu {
  background-color: #f6f7f2;
  width: 100%;
  border-color: darkgrey;
  border-width: 1px;
  border-style: dotted;
}

.tt-selectable {
  cursor: pointer;
}

  /* GRAPH */
#neb-enzyme-chart {
  width: 88%;
  margin-top: 60px;
  display: inline-block;
}

.bluish {
  color: #0088CC;
}

.oligo-table-bluish {
  color: #0088CC;
  cursor: pointer;
}

#landing-page-file-input {
  display: none;
}

#landing-page-file-to-upload {
  z-index: 1;
  pointer-events: none;
}

.modal-btn,
.modal-btn:hover {
  margin-right: 5px;
  color: #0088CC;
  background-color: inherit;
  border: none;
}

.prefs-modal-item {
  list-style-type: none;
}

.prefs-modal-item label {
  display: block;
  font-weight: inherit;
}

.prefs-header {
  float: left;
}

.prefs-help-icon {
  margin-left: 3px;
}

.graphical-help-icon {
  margin-top: 10px;
}

.modal-content-btns {
  text-align: left;
}

#prefs-modal-error-region,
#feedback-modal-error-region,
#winner-modal-error-region {
  overflow: hidden;
  height: 35px;
  padding: 5px;
  color: red;
  font-weight: bold;
  margin-top: 10px;
  font-size: large;
}

#min-orf-length {
  width: 160px;
}

#region-bp-start,
#region-bp-end {
  width: 76px;
}

.error-background {
  background-color: #ff9290;
  border-width: 4px;
  border-style: double;

}

@media screen and (min-width: 768px) {
  .modal-dialog {
    width: 700px; /* New width for default modal */
  }
}

@media screen and (min-width: 992px) {
  .modal-lg {
    width: 950px; /* New width for large modal */
  }
}

#oligo-table thead {
  display: block;
  width: 95%;
}

#oligo-table thead tr {
  display: inline-table;
  width: 100%;
}

#oligo-table thead th {
  background-color: inherit;
  font-weight: inherit;
  border: none;
  font-weight: bold;
  padding-left: 5px;
}

#oligo-list {
  width: 100%;
  overflow-y: scroll;
  max-height: 100px;
  display: inline-block;
  border-collapse: separate;
  border-spacing: 3px;
}

#oligo-list tr {
  display: inline-table;
  width: 100%;
}

#oligo-list td {
  border-style: solid;
  border-width: 1px;
  border-color: lightgray;
  background-color: inherit;
}

.disabledDiv {
  pointer-events: none;
  opacity: 0.4;
}

.enableDiv {
  pointer-events: visible;
  opacity: 1;
}

#edit-oligo-table {
  width: 100%;
}

#edit-oligo-table thead {
  display: block;
  width: 95%;
}

#edit-oligo-table thead tr {
  display: inline-table;
  width: 100%;
}

#edit-oligo-table thead th {
  background-color: inherit;
  font-weight: inherit;
  border: none;
  font-weight: bold;
}

#edit-oligo-list-body {
  width: 100%;
  overflow-y: scroll;
  border-spacing: 3px;
}

#edit-oligo-list-body tr {
  display: inline-table;
  width: 95%;
}

.oligo-name, .oligo-seq {
  border-style: none;
  width: 100%;
}

.oligo-name-td, .oligo-name-th {
  min-width: 50%;
}

img#add-oligo-btn{
  width: 25px;
  opacity: 0.5;
  cursor: pointer;
}

.oligo-seq-td,
.oligo-seq-th {
  width: 50%;
}

.btn-orange,
.btn-orange:active,
.btn-orange:focus{
  color: white;
  font-weight: bold;
  background-color: #F58025;
  border-radius: 6px;
  padding: 6px 40px;
  box-shadow: none;
}

.btn-orange:hover{
  color: white;
  background-color: #cb521e;
}

.btn-orange:disabled{
  background-color: lightgray;
}

::-webkit-scrollbar {
  -webkit-appearance: none;
  width: 7px;
}

::-webkit-scrollbar-thumb {
  border-radius: 4px;
  background-color: rgba(0, 0, 0, .5);
  -webkit-box-shadow: 0 0 1px rgba(255, 255, 255, .5);
}

#feedback-modal-text, #winner-text {
  width: 100%;
}

#feedback-modal-name, #feedback-modal-email, #winner-name, #winner-email {
  margin-bottom: 20px;
  width: 100%;
}

.feedback-field {
  width: 100%;
}
.main-page-btn {
  margin-top: 15px;
  font-weight: bold;
}

#file-upload {
  width: 95%;
  max-width: 414px;
}

#landing-workarea {
  margin-left: 10px;
}

#tool-header,
#tool-footer {
  display: block;
  position: relative;
  z-index: 1;
}

#nebfooter {
  display: block;
}

.lightgray {
  color: lightgray;
}

  /******************************************************************************/
  /****************************** Index Page CSS ********************************/
  /******************************************************************************/
#layout {
  display: flex;
  justify-content: space-between;
}

#sidebar {
  background: #F6F7F1;
  box-sizing: border-box;
  flex: 0 0 20%;
  padding-left: 0;
}

#workarea {
  box-sizing: border-box;
  flex: 1 1;
  padding: 0 0 30px 0px;
}

/******************************************************************************/
/**************************** Landing Sidebar CSS *****************************/
/******************************************************************************/
#landing-sidebar {
  background-color: #f6f7f2;
  box-sizing: border-box;
  display: flex;
  flex-direction: column;
  justify-content: flex-start;
  margin-left: 0;
  max-height: 100%;
  padding-top: 3.5em;
}

#landing-sidebar-title-row {
  flex: 0 0 auto;
  padding-left: 15px;
}

#landing-sidebar-caption {
  margin: 0 35px 0 0;
}

#landing-sidebar-projects-menu {
  flex: 1 1 auto;
  overflow-x: hidden;
  overflow-y: auto;
  padding-bottom: 1.5em;
}

.landing-sidebar-menu-btn {
  background-color: #f6f7f2;
  border-left: none;
  border-right: none;
  padding: 10px;
}

.landing-sidebar-menu-btn-chkbx {
  border-radius: 0;
  cursor: pointer;
  height: 20px;
  margin-left: 5px;
  margin-right: 5px;
  margin-top: 10px;
}

img.clear-enzyme{
  width: 19px;
  margin-right: 7px;
  opacity: 0.5;
  cursor: pointer;
}

img.clear-enzyme:hover{
  opacity: 1;
}

.enzyme-list{
  list-style-type:none;
  margin-top: 5px;
}

#project-list {
  margin: 0;
  overflow-y: visible;
}

#project-list > li {
  display: flex;
  margin: 0;
}

#G {
  background: #000; border: 1px dashed black;
  padding-left: 0;
  height: 600px;
}

.project-btn > .landing-sidebar-menu-btn  {
  border: none;
  border-bottom: 1px solid #ddd;
  border-radius: 0;
  flex: 1 1;
  text-align: left;
}
.project-btn > .landing-sidebar-menu-btn-chkbx {
  flex: 0 0 auto;
}

#project-list .landing-sidebar-menu-btn:hover {
  background-color: #E1E2E2;
  font-weight: bold;
  cursor: pointer;
}

#landing-sidebar-disable-cookies-checkbox {
  flex: 0 0 auto;
  padding-left: 15px;
  margin-top: 1em;
}

/******************************************************************************/
/***************************** Landing Page CSS *******************************/
/******************************************************************************/
#landing-instructions {
  margin-top: 35px;
  max-width: 50em;
  text-align: left;
}

#landing-workarea {
  margin-left: 10px;
}

.sequence-specification-step {
  color: #022D4F;
  font-size: x-large;
  margin-top:1.6em;
  white-space: nowrap;
}

#landing-page-genbank-input {
  max-width:327px;
  width: 78%;
}

#project-name {
  margin-left: 20px;
  width: 20em;
}

.btn-group > .btn {
  color: #5C5C5C;
  font-size: 11pt;
  font-weight: bold;
  padding: 6px 24px;
}

.clear-btn{
  color: #5C5C5C;
  font-size: 11pt;
  font-weight: bold;
  display: inline-block;
  text-align: center;
  cursor: pointer;
  border-radius: 4px;
  border: 1px solid transparent;
  border-color: #CCC;
}

.dismiss-btn{
  color: #5C5C5C;
  font-size: 11pt;
  display: inline-block;
  text-align: center;
  cursor: pointer;
  border-radius: 4px;
  border: 1px solid transparent;
  border-color: #CCC;
  height: 25px;
  margin-top: 10px;
}

#seq-input-type-btn-bar {
  margin-left: 20px;
}

#seq-input-panel {
  margin: 5px 0 0 20px;
  padding: 0;
}

#seq-input-pane-text {
  width: 95%;
}

#seq-input-pane-text >textarea {
  max-width: 100%;
  min-width: 200px;
}

#seq-input-pane-genbank {
  color: #5C5C5C;
  width: 95%;
}

#seq-input-pane-genbank a {
  color: inherit;
}

#set-preferences-row {
  margin-left: 20px;
}

#prefs-btn {
  color: #5C5C5C;
  font-weight: bold;
  margin-left: 1.5em;
}

.error-modal-title{
  white-space: nowrap;
}

input.bootstrap-combobox{
  width: 100%;
  border: 1px solid lightgrey;
  padding: 6px;
  border-radius: 4px;
  text-indent: 0.4em;
  box-shadow: inset 0 1px 1px rgba(0, 0, 0, .075);
}

input.bootstrap-combobox::placeholder{
  color: #999999;
}

input.bootstrap-combobox:focus{
  outline: none;
}

.bootstrap-combobox-container > div > div > ul{
  width: 100%;
  background-color: #f6f7f2;
}
/******************************************************************************/
/**************************** Project SidebarCSS ******************************/
/******************************************************************************/
#project-sidebar {
  background-color: white;
}

#project-sidebar-tabs button {
  border-left: none;
  border-radius: 0;
  border-right: none;
  font-weight: bold;
}

#project-sidebar-tabs .btn-deselected {
  background-color: #f6f7f2;
}

#project-sidebar-tabs .btn-deselected:hover {
  background-color: gray;
  color: white;
  opacity: 0.5;
}

#project-sidebar-tabs .btn-selected {
  background-color: #F58025;
  color: white;
}

#project-sidebar-summary {
  background-color: #f6f7f2;
  padding: 10px;
}

#project-sidebar-analysis-info,
#project-sidebar-seq-info li {
  list-style: none;
}

#project-sidebar-start-over{
color: #555;
  font-weight: bold;
  margin: 0.5em 0;
  width: 200px;
}
#project-sidebar-edit-prefs{
  color: #555;
  font-weight: bold;
  margin: 0.5em 0;
  width: 60px;
  float:right;
}

#flank-ok{
  color: #555;
  font-weight: bold;
  margin: 0 0;
  width: 60px;
}

#project-sidebar-btns {
  display: flex;
  flex-direction: column;
  justify-content: space-around;
  margin: 0 1em 1em;
  padding: 12px 5px 2px 5px;
}

.project-sidebar-view-details {
  color: #0088CC;
  font-size: 13px;
  margin-left: 25px;
  cursor: pointer;
}

#analysis-warning-modal-continue-btn {
  float: right;
}

/******************************************************************************/
/***************************** Graphical View CSS *****************************/
/******************************************************************************/

.main-page-header{
  font-weight: bold;
}

.zoom-container {
  width: auto;
  float: left;
}

#orf-legend-container {
  margin-bottom: 10px;
}

.graphic-container {
  width: 100%;
  height: 600px;
}

.graphic-warning-dot-hide{
  display: none;
  text-align: center;
  margin-top: 20px;
  border-top: 2px dotted #000;
}

.graphic-warning-dot-show{
  display: block;
  text-align: center;
  margin-top: 20px;
  border-top: 2px dotted #000;
}

#graphic-warning-label{
  color: #ec6722;
  margin: 5px;
  font-weight: lighter;
  font-family: Arial, Helvetica, sans-serif;
}

.orf-graphic-container {
  width: 100%;
  height: 900px;
  overflow: auto;
}

.zoom-btn {
  margin-bottom: 1px;
  float: left;
  font-size: medium;
  margin-left:-15px;
}

.custom-zoom-column {
  width: auto;
  margin: 2px;
  padding: 0px;
}

.list-zero-cut{
  margin-top: 5px;
  cursor: pointer;
}

.custom-zoom-field {
  text-align:center;
}
/********** Sidebar CSS **********/
.orf-details-summary {
  padding-left: 16px;
  list-style-type: disc;
  margin:10px 0;
}

.sequence-information{
  padding:0;
  list-style-type: none;
}
/******** End Sidebar CSS ********/



/********** Legend CSS **********/
.legend {
  background-color: #f6f7f2;
  padding: 10px 20px;
  margin-bottom: 15px;
}

.legend-site {
  background-color: #f6f7f2;
  width: 100%;
  padding-left: 20px;
  margin-bottom: 15px;
}

.legend-column {
  padding: 0px;
  overflow-x: visible;
}

.cutters {
  background-color: #f6f7f2;
  width: 50%;
  float: left;
  padding: 10px 0px 10px 2px;
  margin-bottom: 15px;
}

.left-align-list {
  list-style: none;
  padding: 0;
}

.list-meth-ul li{
   display:inline;
   padding: 0;
}

.left-align-list li label{
  font-weight: normal;
  margin-bottom: 0;
}

.radio-buttons{
  margin-left: 1.8em;
  text-indent: -0.3em;
}

.radio-buttons input[type="radio"]{
  display: none;
}

#cleavage-code-filters li span{
  padding-left: 5px;
}

.supplier-code-filters {
  padding-left: 0.8em;
  text-indent: -0.8em;
}

.supplier-code-filters li span:nth-child(2),
.methylation-list li span:first-child{
  padding-left: 5px;
}

.methylation-list {
  padding-left: 1em;
  text-indent: -1em;
}

.other-supplier-color {
  color: #768f2c;
}

.not-commercially-available-color {
  color: #7f7f7f;
}

.cpg:before{
  content: '*';
  font-family: 'Glyphicons Halflings';
  font-size: 8pt;
  color: black;
}

.dam-dcm:before{
  content: '#';
  font-family: 'Glyphicons Halflings';
  color: black;
}

.ambigous:before{
  content: '()';
  font-family: 'Glyphicons Halflings';
  color: black;
}

.display-info{
  color: gray;
}
/********** End Legend CSS **********/

/********** Download Button CSS **********/
.download-tool {
  margin-bottom: 0;
}

.download-resolution {
  margin-left:10px;
}

.download-tool > .main-page-btn {
  margin: 25px 15px 0 0;
}

/********** Enzyme Modal CSS **********/
.rec-seq-text{
  font-family: monospace;
}

.show{
  display: block;
}

.hide{
  display: none;
}

#enzyme-modal-header{
  border-bottom: none;
  padding-left: 30px;
}

#enzyme-modal-header-container{
  width: 870px;
  border-bottom: 3px solid #022e4f;
}

#enzyme-modal-header-container .modal-title {
  margin-left: 0;
}

#enzyme-modal-title-name,
#enzyme-modal-title-number{
  display: inline;
}

#enzyme-modal-body{
  padding-top: 0px;
}

#sites-modal-ref-number,
#site-modal-ref-number,
#enzyme-modal-ref-number{
  margin-top: 20px;
  margin-right: 10px;
  font-size: 15px;
}

#features-list{
  padding: 0px 0px 0px 15px;
  list-style-type: disc;
}

img#neb-enzyme-chart{
  width: 50%;
}

.enzyme-modal-table-row{
  margin-bottom: 30px;
}

.modal-table thead tr th.percent-activity-col{
  text-align: center;
  color: #616161;
  border-top: none;
}

.modal-table thead tr th.percent-activity-col.one-one-col{
  background-color: #e2c441;
  border-left: none;
}

.modal-table thead tr th.percent-activity-col.two-one-col{
  background-color: #7daace;
}

.modal-table thead tr th.percent-activity-col.three-one-col{
  background-color: #d0314e;
}

.modal-table thead tr th.percent-activity-col.cs-col{
  background-color: #0f8e73;
}

#buffer-neoschizomer-description{
  margin-left: 15px; 
  margin-top: 5px;
}

.neoschizomer{
  font-weight: bold;
  font-style: italic; 
  font-size: 16px; 
  font-family: monospace;
}
/******** End Enzyme Modal CSS ********/

/***** Site Sequence Modal CSS *******/

.site-sequence-details-table{
  max-height: calc(100vh - 130px);
  overflow-y: auto;
}

#silent-muta-site-modal-header,
#flank-enzymes-modal-header,
#sites-modal-header,
#site-sequence-modal-header{
  border-bottom: none;
  padding-left: 30px;
}

#silent-muta-site-modal-header-container,
#flank-enzymes-modal-header-container,
#sites-modal-header-container,
#site-sequence-modal-header-container{
  width: 870px;
  border-bottom: 3px solid #022e4f;
}

#silent-muta-site-modal-header-container,
#flank-enzymes-modal-header-container,
#sites-modal-header-container,
#site-sequence-modal-header-container .modal-title {
  margin-left: 0;
}

#silent-muta-site-sequence-modal-container{
  height: 140px;
  overflow-y: auto;
}

#site-sequence-modal-container{
  overflow-y: auto;
}

.site-sequence-enzyme-modal-header-container{
  overflow-y: auto;
  margin-top: 10px;
  padding-right: 0px;
  max-height: 300px;
}

.compatible-sites{
  width: 12%;
}

#site-sequence-modal-table th{
  border-top: 1px solid darkgray;
}

#site-sequence-modal-table thead tr{
  display: table;
}

#enzyme-modal-table th {
  border-top: 1px solid darkgray;
}

#enzyme-iso-modal-table th {
  border-top: 1px solid darkgray;
}

.modal-methylation-col{
  width: 25%;
}

.modal-producing-enzyme{
  width: 18%;
}

.modal-producing-specificity{
  width: 36%;
}

.modal-producing-compatible{
  width: 15%;
}

.site-sequence-enzyme-modal-table{
  margin-bottom: 0px;
}

#site-sequence-enzyme-modal-container{
  height: 240px;
  overflow-y: scroll;
  padding-right: 0px;
}

#site-sequence-enzyme-modal-table {
  border-collapse: separate;
  border-spacing: 0;
  padding-left: 0px;
  padding-right: 0px;
}

#site-sequence-enzyme-modal-table th{
  border-right: 0px;
  border-top: 1px solid darkgray;
}

#site-sequence-enzyme-modal-table td{
  border-right: 0px;
}

#site-sequence-enzyme-modal-table th:last-child,
#site-sequence-enzyme-modal-table td:last-child {
  border-right: 1px solid darkgray;
}

.none-padding{
  padding-left: 15px;
}

#silent-muta-site-modal-title-name,
#flank-enzymes-modal-title-name,
#sites-modal-title-name,
#site-sequence-modal-title-name,
#site-sequence-modal-title-number{
  display: inline;
}

#silent-muta-modal-body,
#sites-modal-body,
#site-sequence-modal-body{
  padding-top: 0px;
  max-height: calc(100vh - 130px);
  overflow-y: auto;
}

.site-sequence-bracket{
  text-decoration: underline;
}

.site-sequence-squarebracket{
  color: red;
}

.unpredict-methyl{
  background-color: lightgray;
  margin: 10px 15px 5px 0px;
  padding: 5px;
  align-items: center;
}

.warning{
  font-size: x-large;
  cursor: pointer;
  color: #ebc015;
  padding-left: 0px;
  margin-left: 5px;
}

.question{
  font-size: medium;
  cursor: pointer;
  color: #022e4f;
  padding-left: 0px;
  vertical-align: middle;
  float: right;
  margin: 10px 5px 0px 0px;
}

.unpredict-methyl-label{
  margin-left: 5px;
  align-self: center;
}

/****** End Site Sequence Modal CSS ******/

/******************************************************************************/
/*************************** End Graphical View CSS ***************************/
/******************************************************************************/



/******************************************************************************/
/*************************** Sequence CSS *************************************/
/******************************************************************************/
#main-page-panel-sequence-table td + td{
  padding-left: 60px;
  font-family: "Lucida Console", monospace;
}

#main-page-panel-sequence-table td:first-child{
  text-align: right;
}

pre {
    border: 0;
    background-color: transparent;
}

/******************************************************************************/
/************************* End Sequence CSS ***********************************/
/******************************************************************************/


/******************************************************************************/
/************************* Enzyme List CSS ************************************/
/******************************************************************************/

/** Legacy Enzyme List CSS**/
/* ENZYMES TABLE */
.enzymes-table-container{
  padding: 0 0 0 30px;
  margin-left: -19px;
}

.enzyme-table-header-container{
  overflow-y:scroll;
  margin-top:20px;
}

#enzyme-table-container{
  height:500px;
  overflow-y:auto;
  border: none;
  padding-left: 0px;
  padding-right: 0px;
}

.enzymes-table-header{
  margin-bottom: 0px;
}

#enzymes-table thead th,
#enzymes-table td{
  border-width: 1px 1px 1px 0;
}

#enzymes-table .enzyme-row-expanded > th{
  background-color: white;
}

.enzymes-table-head {
  border: 0 !important;
}

.enzymes-table-head tr {
  border-top: 0px solid #BABABA;
  border-width: 1px 0 0 1px;
}

#enzymes-table th.enzymes-table-col-enzyme-sites,
#enzymes-table td.enzymes-table-col-enzyme-sites{
  border-right: none !important;
  border-left: 1px solid #BABABA !important;
}

.enzyme-row-selected{
  border-bottom: 1px solid black;
  border-left: 1px solid black;
}

.enzyme-row-expanded{
  background-color: white !important;
  display:none;
}

.enzyme-row-unselected-top{
  border-top: 1px solid black;
  border-left: 1px solid black;
}

.enzyme-row-unselected{
  border-left: 1px solid black;
  border-top: 1px ridge #D3D3D3
}

.enzyme-row-unselected-bottom{
  border-bottom: 1px solid black;
  border-left: 1px solid black;
}

#enzymes-table tr {
  display: table;
}

#fragments-table thead tr {
  display: table;
}

.glyphicon-menu-down,
.glyphicon-menu-up
{
  cursor: pointer;
}

.cleavage-marker{
  width: 6px;
}

/* ENZYME SITES SUB TABLE */
#enzyme-sites-table-header{
  padding: 8px 0px 8px 16px;
  border-left: none;
  border-right: none;
}

#enzyme-sites-table-header tbody td{
  font-weight: normal;
}

#enzyme-sites-table td{
  padding: 4px 8px 0px 8px;
}

#enzyme-sites-table thead th:last-child,
#enzyme-sites-table td:last-child{
  border-width: 0;
}

.enzyme-sites {
  width: 100%;
}

.sub-enzyme {
    display:none;
}

.enzyme-sites-table {
  display: table;
  margin: 10px 0;
}

.enzyme-sites-table-col-cut-region {
  min-width: 130px;
  width: 10%;
}

.enzyme-sites-table-col-flanking-sequence .enzyme-sites-table-flanking-sequence-data {
  display: inline;
}

#list-flank-table{
  height: 500px; 
  overflow-y: auto;
}

.list-flank-table-header{
  overflow-y: scroll;
  margin-top: 10px;
}

.flank-table-header{
  margin-bottom: 0px;
}

.flank-overhang-col{
  width: 20%;
}

td.flank-enzyme-col{
  cursor: pointer;
}

.flank-enzyme-col{
  width: 15%;
}

.flank-specificity-col{
  width: 37%;
}

td.flank-specificity-col{
  font-family: "monospace";
}

.flank-compatible-site-col{
  width: 28%;
}

.enzyme-sites-table-flanking-sequence-data-inner {
  display: inline;
  padding-left: 8px;
  font-family: "Lucida Console", monospace;
}

.enzyme-sites-table-col-methylation-site {
  min-width: 90px;
  width: 1%;
}

.pointer {
  cursor: pointer;
}

.enzyme-sites-recognition-sequence-text {
  color: red;
}

/* ENZYME LIST */

.enzymes-table-head {
  border: 1px solid gray;
}

.enzyme-sites-table-row{
  background-color: white;
  font-size: 14px;
}

.enzymes-table-col-num-cuts {
  text-align: left;
  width: 8%;
  min-width: 60px;
}

.enzymes-table-col-enzyme-sites {
  min-width: 15px;
  width: 1%;
}

.enzymes-iso-table-col-enzyme-name{
  cursor: pointer;
} 

.enzymes-table-col-enzyme-name {
  text-align: left;
}

td.enzymes-table-col-enzyme-name {
  cursor: pointer;
}

th.enzymes-table-col-enzyme-name span:first-child{
  margin-left: -13px;
}

.enzymes-table-col-recognition-sequence {
  text-align: left;
  width:45%;
}

.cuts-col{
  width: 8%;
}

.enzymes-table-col-methylation-sensitivity {
  text-align: center;
  width: 28%;
  min-width: 90px;
}

#enzyme-modal-body-row {
  padding: 0px 45px 0px 15px;
}

#enzyme-sub-sites-table-row {
  background-color: white;
  font-size: 14px;
}

#enzyme-modal-body.modal-body {
  padding-left: 0;
}
/** End Legacy Enzyme List CSS**/

#n-cutters-container,
#min-max-container{
  display: inline-block;
}

#n-cutters-container{
  padding-right: 20px;
}

#min-max-container{
  padding-right: 70px;
}

#neb-enzyme-chart-half{
  width: 90%;
  float: right;
}

#neb-enzyme-modal-chart-half{
  width: 25%;
  float: right;
}

/** Enzyme Table Under 1280p CSS **/
@media
only screen and (max-width: 1272px),
(min-device-width: 768px) and (max-device-width: 1272px) {

  #enzyme-sites-table thead,
  #enzyme-sites-table tbody,
  #enzyme-sites-table th,
  #enzyme-sites-table td,
  #enzyme-sites-table tr{
    display: block;
  }

  #enzyme-sites-table thead tr{
    position: absolute;
    top: -9999px;
    left: -9999px;
  }

  #enzyme-sites-table tr td.enzyme-sites-table-col-cut-region,
  #enzyme-sites-table tr td.enzyme-sites-table-col-flanking-sequence,
  #enzyme-sites-table tr td.enzyme-sites-table-col-methylation-site{
    padding-right: 0px;
    border-right: 1px solid black;
  }

  th.enzymes-table-col-num-cuts,
  td.enzymes-table-col-num-cuts{
    padding-left: 8px !important;
  }

  #enzyme-sites-table tr td.enzyme-sites-table-col-flanking-sequence{
    width: 0px;
  }

  .enzyme-sites-table-col-flanking-sequence{
    min-width: 0px;
  }

  #enzyme-sites-table td{
    position: relative;
    background-color: lightgrey;
    font-size: 11pt;
    padding-left: 30%;
    border-right: none;
    white-space: nowrap;
  }

  #enzyme-sites-table td:before{
    position: absolute;
    top: 4px;
    left: 8px;
    width: 45%;
    padding-right: 10px;
    white-space: nowrap;
  }

  #enzyme-sites-table td span{
    padding-left: 8px;
  }

  #enzyme-sites-table td:nth-of-type(1):before{
    content: "Cut Position";
    font-weight: bold;
  }
  #enzyme-sites-table td:nth-of-type(2):before{
    content: "Site With Flanks (5' ’ 3')";
    font-weight: bold;
  }
  #enzyme-sites-table td:nth-of-type(3):before{
    content: "CpG";
    font-weight: bold;
  }
  #enzyme-sites-table td:nth-of-type(4):before{
    content: "Dam";
    font-weight: bold;
  }
  #enzyme-sites-table td:nth-of-type(5):before{
    content: "Dcm";
    font-weight: bold;
  }
  #enzyme-sites-table td:nth-of-type(6):before{
    content: "EcoBI";
    font-weight: bold;
  }
  #enzyme-sites-table td:nth-of-type(7):before{
    content: "EcoKI";
    font-weight: bold;
  }
}
/** End Enzyme Table Under 1280p CSS **/

/******************************************************************************/
/************************* End Enzyme List CSS ************************************/
/******************************************************************************/


/******************************************************************************/
/************************* Custom Digest CSS **********************************/
/******************************************************************************/

.enzyme-HF{
  vertical-align: middle !important;
  background-color: #FFF !important;
}

input[type=checkbox][disabled] + label {
    color: #ccc;
}

.btn-group-container{
  margin-bottom: 30px;
  width: 100%;
}

.custom-digest-btn-group{
  width: 20%;
  min-width: 140px;
}

.custom-digest-enzymes-table-container{
  padding-right: 0px;
}

.custom-digest-enzymes-selection-table-container{
  padding-right: 0px;
  padding-left: 0px;
}

.cpg-checkbox, .dcm-checkbox, .ecobi-checkbox, 
.dam-checkbox, .ecoki-checkbox,
.gel-cpg-checkbox, .gel-ecobi-checkbox, .gel-dam-checkbox, 
.gel-ecoki-checkbox, .gel-dcm-checkbox{
  float: left;
  width: 100px;
}

.gel-cpg-checkbox{
  float: left;
}

.methylation-ul{
  list-style-type: none;
  margin: 0;
  padding: 0;
  overflow: hidden;
  width: 320px;
}

.marker-list{
  margin:10px 0 0 0
}
/********** Create Custom Digest CSS **********/

.custom-digest-dropdown-container{
  margin-bottom: 10px;
}

.custom-digest-dropdown{
  width: 50px;
}

.custom-digest-dropdown-option{
  padding-left: 10px;
  padding-right: 10px;
}

.select-option-indent{
  padding-left: 21px;
}

.select-option-enzymes{
  padding-left: 5px;
  padding-right: 5px;
}

.site-length-option{
  width: 60px;
  padding-left: 18px;
}

@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
  .select-option-indent{
    padding-left: 19px;
  }

}

#custom-digest-flank-min,
#custom-digest-flank-max,
#custom-digest-flank-margin {
  width: 4em;
}

.custom-digest-filter{
  margin-top: 10px;
}

.sorting-arrow{
  color: lightgray;
}

/********** Enzyme Search CSS **********/
#enzyme-search-btn{
  border: 0;
  background: transparent;
}
.descrip-text{
  color: gray;
}

.search-container{
  width: 66.66%;
  margin-left: 15px;
  margin-bottom: 20px;
}


.search-textbox{
  border-right: none;
  box-shadow: none;
  -webkit-appearance: none;
}

.search-btn{
  color: #cccccc;
  padding: 0;
}

.form-control:focus{
  border-color: #cccccc;
  -webkit-box-shadow: none;
  box-shadow: none;
}

.form-control1:focus{
  border-color: #cccccc;
  -webkit-box-shadow: none;
  box-shadow: none;
}

.glyphicon-search {
  -moz-transform: scaleX(-1);
  -o-transform: scaleX(-1);
  -webkit-transform: scaleX(-1);
  transform: scaleX(-1);
  filter: FlipH;
  -ms-filter: "FlipH";
}

/******** End Enzyme Search CSS ********/
/******** Start Loading CSS *********/
#overlay {
    position: fixed;
      display: none;
      width: 100%;
      height: 100%;
      top: 0;
      left: 0;
      right: 0;
      bottom: 0;
      background-color: rgba(0,0,0,0.1);
      z-index: 2;
      cursor: pointer;
}

#text{
  position: absolute;
  top: 50%;
  left: 50%;
  font-size: 50px;
  color: white;
  transform: translate(-50%,-50%);
  -ms-transform: translate(-50%,-50%);
}

.lds-roller {
  display: inline-block;
  position: relative;
  width: 64px;
  height: 64px;
  position: absolute;
  top: 50%;
  left: 50%;
}
.lds-roller div {
  animation: lds-roller 1.2s cubic-bezier(0.5, 0, 0.5, 1) infinite;
  transform-origin: 32px 32px;
}
.lds-roller div:after {
  content: " ";
  display: block;
  position: absolute;
  width: 6px;
  height: 6px;
  border-radius: 50%;
  background: #FFF;
  margin: -3px 0 0 -3px;
}
.lds-roller div:nth-child(1) {
  animation-delay: -0.036s;
}
.lds-roller div:nth-child(1):after {
  top: 50px;
  left: 50px;
}
.lds-roller div:nth-child(2) {
  animation-delay: -0.072s;
}
.lds-roller div:nth-child(2):after {
  top: 54px;
  left: 45px;
}
.lds-roller div:nth-child(3) {
  animation-delay: -0.108s;
}
.lds-roller div:nth-child(3):after {
  top: 57px;
  left: 39px;
}
.lds-roller div:nth-child(4) {
  animation-delay: -0.144s;
}
.lds-roller div:nth-child(4):after {
  top: 58px;
  left: 32px;
}
.lds-roller div:nth-child(5) {
  animation-delay: -0.18s;
}
.lds-roller div:nth-child(5):after {
  top: 57px;
  left: 25px;
}
.lds-roller div:nth-child(6) {
  animation-delay: -0.216s;
}
.lds-roller div:nth-child(6):after {
  top: 54px;
  left: 19px;
}
.lds-roller div:nth-child(7) {
  animation-delay: -0.252s;
}
.lds-roller div:nth-child(7):after {
  top: 50px;
  left: 14px;
}
.lds-roller div:nth-child(8) {
  animation-delay: -0.288s;
}
.lds-roller div:nth-child(8):after {
  top: 45px;
  left: 10px;
}
@keyframes lds-roller {
  0% {
    transform: rotate(0deg);
  }
  100% {
    transform: rotate(360deg);
  }
}

/******** End Loading CSS ******/

/******** Custom Digest Table CSS ********/

#custom-digest-container,
#custom-digest-table-container{
  padding: 0;
}

#custom-digest-table-container{
  border: none;
  padding: 0;
}

#custom-digest-table-container{
  padding: 0;
  height:500px;
  overflow-y:auto;
}

#custom-digest-enzyme-table-container{
  padding: 0;
  max-height:500px;
  overflow-y:scroll;
}

.custom-digest-table-header-container{
  overflow-y: scroll;
}

.custom-digest-selection-table{
  margin-bottom: 0px;
}

#custom-digest-table thead tr > th{
  border-top: 1px solid darkgray;
  border-left: none;
}

#custom-digest-table thead tr > th.select-col{
  border-left: 1px solid darkgray;
  border-right: none;
  text-align: center;
}

#custom-digest-table tbody tr:last-child td{
  border-bottom: 1px solid darkgray;
}

#custom-digest-table td{
  border-left: none;
}

#custom-digest-table thead tr{
  display: table;
}

.custom-digest-table-check{
  width: 8%;
  text-align: center !important;
  border-left: 1px solid darkgray !important;
  border-right: 0px !important;
}

.custom-digest-table-enzyme{
  width: 20%;
}

.custom-digest-table-req-sequence{
  width: 32%;
}

.custom-digest-table-cut{
  width: 8%;
}

#site-sequence-enzyme-modal-table thead tr{
  display: table;
}

#sites-sequence-table tr{
  display: table;
}

#gel-table thead tr{
  display: table;
}

#select-all-checkbox{
  margin: 0px;
}

.custom-digest-text{
  height: 30px;
  vertical-align: revert;
}

.buffTable{
  width: 100%;
}

.buffTableTd{
  width: 25%;
}

#custom-digest-table th:first-child {
  border-right: 0px;
  border-left: 1px solid darkgray;
  text-align: center;
}

#custom-digest-table td.select-col{
  border-left: 1px solid darkgray;
  border-right: none;
  text-align: center;
}

#custom-digest-table tbody tr td{
  padding-top: 0;
}

.select-all-container{
  margin-left: 0px;
}

#custom-digest-table tbody tr td input,
#custom-digest-table tbody tr td label{
  margin: 0;
}

#custom-digest-table tbody tr td.select-col{
  position: relative;
}

#custom-digest-table thead tr > th.select-col,
#custom-digest-table td.select-col{
  width: 6px;
}

#custom-digest-table {
  border-collapse: separate;
  border-spacing: 0;
  padding-left: 0px;
  padding-right: 0px;
}

#custom-digest-table th:last-child {
  border-right: 1px solid darkgray;
}

.select-col{
  width: 5%;
}

.custom-digest-enzyme-col {
  text-align: left;
  width: 15%;
}

td.custom-digest-enzyme-col {
  cursor: pointer;
}

th.custom-digest-enzyme-col{
  padding: 0px;
}

th.custom-digest-enzyme-col span:first-child{
  margin-left: -13px;
}

.top-percent-activity-col{
  width: 28%;
}

#custom-digest-table thead > tr:nth-child(1) > th.top-percent-activity-col{
  text-align: center;
}

#custom-digest-table tbody tr td.percent-activity-col{
  text-align: center;
}

.percent-activity-col{
  width: 7%;
}

#custom-digest-table thead tr th.percent-activity-col{
  text-align: center;
  color: #616161;
  border-top: none;
}

#custom-digest-table thead tr th.percent-activity-col.one-one-col{
  background-color: #e2c441;
  border-left: none;
}

#custom-digest-table thead tr th.percent-activity-col.two-one-col{
  background-color: #7daace;
}

#custom-digest-table thead tr th.percent-activity-col.three-one-col{
  background-color: #d0314e;
}

#custom-digest-table thead tr th.percent-activity-col.cs-col{
  background-color: #0f8e73;
}

/******** End Custom Digest Table CSS ********/


/******** End Create Custom Digest CSS ********/

/******** Custom Digest Enzyme List CSS *****/

#custom-digest-enzymes-table thead th,
#custom-digest-enzymes-table td{
  border-width: 1px 1px 1px 0;
}

#custom-digest-enzymes-table .enzyme-row-expanded > th{
  background-color: white;
}


#custom-digest-enzymes-table th.enzymes-table-col-enzyme-sites,
#custom-digest-enzymes-table td.enzymes-table-col-enzyme-sites{
  border-right: none !important;
  border-left: 1px solid #BABABA !important;
}

#custom-digest-enzymes-table tr {
  display: table;
}

/******** Fragments CSS ********/


#fragments-table {
  border-collapse: separate;
  border-spacing: 0;
  padding-left: 0px;
  padding-right: 0px;
}

#fragments-table th{
  border-right: 0px;
  border-top: 1px solid darkgray;
}

#fragments-table td{
  border-right: 0px;
  border-bottom: 0px;
}

#fragments-table th:last-child,
#fragments-table td:last-child {
  border-right: 1px solid darkgray;
}

#fragments-table tr:last-child td {
  border-bottom: 1px solid darkgray;
}

#fragments-table td:nth-child(2){
  color: #F5802C;
}

#fragments-table-container{
  padding: 0;
  height:500px;
  overflow-y:auto;
}

.fragments-table-header-container{
  padding: 0px;
  overflow-y:scroll;
}

.fragment-table-header{
  margin-bottom: 0px;
}

.fragment-number{
  width: 7%;
}

.fragment-ends{
  width: 30%;
}

.fragment-coordinate{
  width: 17%;
}

.fragment-length{
  width: 16%;
}

.fragment-methyl{
  width: 30%;
}

/******** End Fragments CSS ********/


/******** Gel CSS ********/

#gel-dropdowns{
  display: inline-block;
  width: 100%;
}
#gel-title{
width:10%
}
#gel-type{
  width: 60%;
}

#gel-type-percent{
  width: 25%;
  float: right;
}

.specifications{
  width: 100%;
  padding-right: 0;
}

.see-details-container{
  margin-left: 15px;
}

.see-details-info{
  color: #0088CC;
  cursor: pointer;
}

#gel-graph-container{
  padding-left: 0;
  height: 600px;
}

#gel-table {
  border-collapse: separate;
  border-spacing: 0;
}

#gel-table th{
  border-right: 0px;
  border-top: 1px solid darkgray;
}

#gel-table td{
  border-right: 0px;
}

#gel-table th:last-child,
#gel-table td:last-child {
  border-right: 1px solid darkgray;
}

#gel-table-container{
  padding-right: 0;
  height:500px;
  overflow-y:auto;
}

.gel-table-header-container{
  padding-right: 0;
  overflow-y:scroll;
}

.gel-table-header{
  margin-bottom: 0px;
}

.gel-number-col{
  width: 50px;
}

.gel-ends-col{
  width: 200px;
}

.gel-coordinate-col{
  width: 110px;
}

.gel-length-col{
  width: 70px;
}

.gel-methyl-col{
  width: 106px;
}

#gel-chart{
  width: 100%;
  height: auto;
}

#gel-table td:nth-child(2){
  color: #F5802C;
}

/******** End Gel CSS ********/


/******************************************************************************/
/*********************** End Custom Digest CSS ********************************/
/******************************************************************************/



/******************************************************************************/
/************************* ORF Summary CSS **********************************/
/******************************************************************************/

.orf-summary-btn-group{
  width: 25%;
  min-width: 160px;
}

/********** ORF Selection **********/

.orf-column-width-gene{
  width: 13%;
}

.orf-column-width-product{
  width: 28%;
}

.orf-column-width-aminoacid{
  width: 12%;
}

.orf-column-width-coordinate{
  width: 13%;
}

.orf-column-width-locustag{
  width: 14%;
}

.orf-column-width-proteinId{
  width: 10%;
}

.orf-selection-header-container{
  overflow-y:scroll;
  margin-top:20px;
  padding-right: 0px;
}

#silent-mutagenesis-display-container{
  padding-right: 0px;
  margin-top: 15px;
}


#orf-selection-table-container{
  height:500px;
  overflow-y:auto;
  padding-right: 0px;
}

#add-orf-container{
  padding: 0 0 0 0;
  width:"33.34%";
}

img#add-orf-btn{
  width: 25px;
  opacity: 0.5;
}

img#add-orf-btn:hover{
  opacity: 1;
}

/********** ORF Selection Table **********/

.column {
  float: left;
  width: 100%;
}

#orf-selection-table tr {
  display: table;
}

#orf-selection-table tbody tr {
  width: 100%;
}

#orf-selection-table{
  margin-bottom: 0px;
  padding-left: 0px;
  padding-right: 0px;
  border-collapse: separate;
  border-spacing: 0;
}

#orf-selection-table th:last-child,
#orf-selection-table td:last-child {
  border-right: 1px solid darkgray;
}

#orf-selection-table thead th.orf-index-col{
  border-right: none;
}

#orf-selection-table th{
  font-size: 11pt;
  background-color: lightgrey;
  padding: 4px 8px;
  vertical-align: top;
  border-right: 0px;
  border-top: 1px solid darkgray;
}

#orf-selection-table td{
  padding: 4px 8px 0 8px;
  line-height: 1.5em;
  border-right: 0px;
}


#orf-selection-table tbody tr{
  cursor: pointer;
}

#orf-selection-table thead > tr th.select-orf-col > span{
  margin-left: -25px;
}

.orf-row-selected{
  background-color: #F58025 !important;
  color: white;
}

#orf-selection-table tbody tr:not(.orf-row-selected):hover{
  background-color: gray;
  color: white;
  opacity: 0.5;
}

#orf-selection-table tbody td:nth-child(8),
#orf-selection-table tbody td:last-child:hover{
  color: #0088CC;
}

#orf-selection-table tbody tr.orf-row-selected td:nth-child(8),
#orf-selection-table tbody tr.orf-row-selected td:last-child>a:hover{
  font-weight: normal;
  color: #0088CC;
}

#orf-selection-table tbody tr.orf-row-selected td:nth-child(8),
#orf-selection-table tbody tr.orf-row-selected td:last-child>a{
  font-weight: normal;
  color: #FFF;
}

#orf-selection-table tbody tr:not(.orf-row-selected) td:nth-child(8),
#orf-selection-table tbody tr:not(.orf-row-selected) td:last-child>a:hover{
  font-weight: normal;
  color: #FFF;
}

img.orf-delete{
  width: 19px;
  margin-left: 7px;
  opacity: 0.5;
}

img.orf-delete:hover{
  opacity: 1;
}

.orf-row-selected .glyphicon-pencil{
  opacity: 0.5;
}

.orf-row-selected .glyphicon-pencil:hover{
  opacity: 1;
}

#orf-selection-table thead > tr th.select-orf-col,
#orf-selection-table tbody tr td.select-orf-col{
  border-right: none;
}

.action-col{
  width: 70px;
  padding: 0;
}

th.action-col{
  border-left: none;
}

th.closest-enzyme-col span:last-child{
  position: absolute;
  top: 6px;
  right: 8px;
}

th.closest-enzyme-col span:first-child{
  margin-right: 15px;
}

#orf-selection-table-body  tr td span.glyphicon.glyphicon-pencil{
  color: grey;
  opacity: 0.5;
  margin-left: 8px;
}

#orf-selection-table-body  tr td span.glyphicon.glyphicon-pencil:hover{
  opacity: 1;
}

#orf-selection-table-body  tr.orf-row-selected td span.glyphicon.glyphicon-pencil,
#orf-selection-table-body  tr.orf-row-selected td span.glyphicon.glyphicon-pencil:hover{
  color: white;
}

.col-gene{
  width: 13%;
}

.col-product{
  width: 32%;
}

.col-aminoacid{
  width: 13%;
}

.col-coordinate{
  width: 15%;
}

.col-locustag{
  width: 12%;
}

.col-proteinId{
  width: 15%;
}
/********** End ORF Selection Table **********/

/********** ORF Selection Modal **********/

.orf-modal-label-container{
  margin-bottom: 20px;
}

.orf-modal-textbox{
  width: 90%;
  padding-left: 10px;
  text-align: left;
}

.orf-location-textbox{
  width: 20%;
}

#add-orf-complement{
  margin-top: 30px;
  margin-left: 6px;
}

#edit-orf-complement{
  margin-top: 30px;
  margin-left: 6px;
}

/********** End ORF Selection Modal **********/
/********** End ORF Selection **********/


/********** ORF Details **********/

.protinid{
text-decoration: none;
}

.protinid:hover{
text-decoration: underline;
}

.orf-gene{
margin:0 0 0 5px;
padding-right: 5px;
}


/********** ORF Table**********/
.orf-table-header{
  margin: 0 0 10px 0;
}

.orf-table tbody{
  display: block;
  width: 100%;
  height: 235px;
  overflow-y: scroll;
  padding-right: 20px;
}

.orf-table tr {
  cursor: pointer;
}

.orf-table td:first-child{
  border-right: 1px solid black;
}

.orf-table td{
  padding: 4px 8px 0 8px;
  border: 1px solid lightgrey;
  line-height: 1.5em;
}

.orf-table tr:not(.orf-row-selected){
  background-color: #f6f7f2;
}

.orf-table tr:not(.orf-row-selected):hover {
  background-color: gray;
  color: white;
  opacity: 0.5;
}

.orf-table td:last-child{
  width: 170px;
}
/********** End ORF Table**********/

#orf-details-chart{
  width: 300px;
  height: auto;
}

#orf-details-list{
  padding-left: 15px;
  list-style-type: disc;
  margin-bottom: 15px;
}

#protein-sequence{
  display: inline-block;
  word-break: break-all;
  overflow-wrap: break-word;
}

#orf-details-buttons-container{
  margin-bottom: 20px;
}

.blast-btn{
  color: #5C5C5C;
  font-weight: bold;
  background-color: #f6f7f2;
  border: 1px solid lightgrey;
  margin-right: 10px;
}


.orf-det-sum-cont{
  margin-bottom: 20px;
}

.orf-det-sum-left {
  width: 30%;
}

.orf-det-sum-right {
  width: 70%;
}

.orf-prot-loc {
  max-width: 200px; 
  word-wrap: break-word;
}

.orf-prot-seq-con {
  max-width: 500px;
}

.orf-prot-seq {
  color: gray;
  word-wrap: break-word;
}

/********** End ORF Details **********/

/********* ORF Flanking Sites ********/
.orf-flank{
  width: 100%;
}

#flanking-sites-def {
  padding: 0 0 15px;
}

#flank-min,
#flank-max,
#flank-margin {
  width: 4em;
}

#flanking-img {
  max-width: 100%;
}

/******* End ORF Flanking Sites ******/

/********** Silent Mutagenesis **********/
.seqback{
background-color:#FFFF00;
font-weight:bold;
}
.seqselectback{
color:#FF0000;
font-weight:bold;
text-decoration: underline;
}

.transl{
color: gray;
font-family: monospace;
}

.orf-legend{
  width: 66%;
}

#silent-mutagenesis-list-view{
  height: 500px;
  overflow-y: auto;
}


#silent-mutagenesis-info{
  padding-bottom: 20px;
}

.silentmuta-header{
  margin-bottom: 30px;
}

/********** Silent Mutagenesis Table **********/
#silent-mutagenesis-table {
  border-collapse: separate;
  border-spacing: 0;
}

#silent-mutagenesis-table th{
  border-right: 0px;
  border-top: 1px solid darkgray;
}

#silent-mutagenesis-table td{
  border-right: 0px;
}

#silent-mutagenesis-table th:last-child,
#silent-mutagenesis-table td:last-child {
  border-right: 1px solid darkgray;
}

#silent-muta-site-modal-table thead tr th.sequence-col-before,
#silent-muta-site-modal-table thead tr th.sequence-col,
#silent-muta-site-modal-table tbody tr td.sequence-col-before,
#silent-muta-site-modal-table tbody tr td.sequence-col ,
#silent-mutagenesis-table thead tr th.sequence-col-before,
#silent-mutagenesis-table thead tr th.sequence-col,
#silent-mutagenesis-table tbody tr td.sequence-col-before,
#silent-mutagenesis-table tbody tr td.sequence-col {
  border-right: none;
}

#silent-muta-site-modal-table thead tr th.sequence-col,
#silent-muta-site-modal-table thead tr th.sequence-col-after,
#silent-muta-site-modal-table tbody tr td.sequence-col,
#silent-muta-site-modal-table tbody tr td.sequence-col-after,
#silent-mutagenesis-table thead tr th.sequence-col,
#silent-mutagenesis-table thead tr th.sequence-col-after,
#silent-mutagenesis-table tbody tr td.sequence-col,
#silent-mutagenesis-table tbody tr td.sequence-col-after{
  border-left: none;
}

#silent-muta-site-modal-table thead tr th.sequence-col-before,
#silent-muta-site-modal-table thead tr th.sequence-col,
#silent-muta-site-modal-table tbody tr td.sequence-col-before,
#silent-muta-site-modal-table tbody tr td.sequence-col ,
#silent-mutagenesis-header-table thead tr th.sequence-col-before,
#silent-mutagenesis-header-table thead tr th.sequence-col,
#silent-mutagenesis-header-table tbody tr td.sequence-col-before,
#silent-mutagenesis-header-table tbody tr td.sequence-col {
  border-right: none;
}

#silent-muta-site-modal-table thead tr th.sequence-col,
#silent-muta-site-modal-table thead tr th.sequence-col-after,
#silent-muta-site-modal-table tbody tr td.sequence-col,
#silent-muta-site-modal-table tbody tr td.sequence-col-after,
#silent-mutagenesis-header-table thead tr th.sequence-col,
#silent-mutagenesis-header-table thead tr th.sequence-col-after,
#silent-mutagenesis-header-table tbody tr td.sequence-col,
#silent-mutagenesis-header-table tbody tr td.sequence-col-after{
  border-left: none;
}

#silent-muta-site-modal-table tr,
#silent-mutagenesis-table tr{
  background-color: white;
}

#silent-mutagenesis-table tr {
  display: table;
}

#flank-enzymes-modal-table {
  border-collapse: separate;
  border-spacing: 0;
}

#flank-enzymes-modal-table th{
  border-right: 0px;
  border-top: 1px solid darkgray;
}

#flank-enzymes-modal-table td{
  border-right: 0px;
  border-top: 0px;
  border-bottom: 0px;
}

#flank-enzymes-modal-table thead tr{
  display: table;
}

#flank-enzymes-modal-table th:last-child,
#flank-enzymes-modal-table td:last-child {
  border-right: 1px solid darkgray;
}

#flank-enzymes-modal-table td.overhang-col{
  text-align: center;
}

#silent-muta-site-modal-table tbody td,
#flank-enzymes-modal-table tbody td,
#silent-mutagenesis-table tbody td{
  border-bottom: 1px solid lightgray;
}


#prime-five-table th{
  border-top: 1px solid darkgray;
}

#prime-three-table th{
  border-top: 1px solid darkgray;
}

.enzyme-col {
  width: 10%;
}

td.enzyme-col{
  cursor: pointer;
}

.site-position-col{
  width: 8%;
}

.sequence-col-before{
  width: 5%;
}

.recut-col{
  width: 6%;
}

.specificity-col{
  width: 30%;
}

td.specificity-col,
td.sequence-col{
  font-family: "monospace";
}

th.sequence-col span{
  margin-left: -40px;
}

.sequence-col{
  width: 37%;
}

/* .sequence-col-after{
  width: 5%;
} */

.recut-col{
  width: 6%;
}

.silentmuta-header-table{
  width: 100%
}

.silentmuta-header{
  margin-bottom: 0px;
}

.silentmuta-header-container{
  overflow-y: scroll;
  margin-top: 10px;
}

#silent-muta-site-modal-table tbody tr td.sequence-col,
#silent-muta-site-modal-table tbody tr td.recut-col,
#silent-mutagenesis-table tbody tr td.sequence-col,
#silent-mutagenesis-table tbody tr td.recut-col{
  text-align: left;
}

.yellow-background{
  background-color: #ffff99;
}

.red-underline{
  color: red;
  text-decoration: underline;
}

.recut-btn{
  cursor: pointer;
  opacity: 0.5;
}

.recut-btn:hover{
  opacity: 0.75;
}

.recut-btn:active{
  opacity: 1;
}
/********** End Silent Mutagenesis Table **********/

/********** End Silent Mutagenesis **********/

/******************************************************************************/
/************************* End ORF Summary CSS **********************************/
/******************************************************************************/



/******************************************************************************/
/******************************** Modal CSS ***********************************/
/******************************************************************************/

.decription-txt{
  padding-left: 30px;
  margin: 0px;
  font-size: 18px;
}

.modal-dialog {
  color: #515151;
}

.modal-dialog .close {
  opacity: 0.5;
}

.modal-dialog .close:hover {
  opacity: 1;
}

.close:focus{
  outline: none;
}

.modal-title {
  color: #022D4F;
  margin-left: 15px;
}

.modal-header {
  border-bottom: none;
}

.modal-footer {
  border-top: none;
}

.modal-row {
  display: flex;
}

.modal-column {
  box-sizing: border-box;
}

.modal-column + .modal-column {
  border-left: 1px solid #CFCFCD;
}

@media (min-width: 1048px) {
  .modal-xl {
    width: 1024px;
  }
}

.prefs-modal-item {
  margin-left: 22px;
  text-indent: -22px;
}
.sequence-modal-item {
  margin-top: 22px;
}

.ignore-modal-item {
  margin-left: 17px;
}

.prefs-modal-item input[type="radio"] + label,
.prefs-modal-item input[type="checkbox"] + label  {
  display: inline;
}

.modal-medium-small{
  width: 448px;
}

img.export-preview {
  max-width: 100%;
}

.sequence-container {
  overflow: scroll;
}

.row-header-arrow{
  color: lightgray;
  cursor: pointer;
}

.icon-rotate-90{
  transform: rotate(90deg);
}

.custom-table{
  margin-top: 10px;
  margin-bottom: 10px;
  width: 98%;
  max-height: calc(100vh - 130px);
  overflow-y: auto;
  background: #FFF;
}

.custom-table-header {
  display: table-header-group;
  font-weight: bold;
  color: #5C5C5C;
  background-color: lightgrey;
  padding: 4px 8px;
  vertical-align: top;
  border: 1px solid #BABABA;
  text-align: left;
}

.custom-table-header-cell {
  display: table-cell;
  padding: 10px;
  text-align: justify;
  border-left: 1px solid #BABABA;
  border-bottom: 1px solid #BABABA;
  border-top: 1px solid #BABABA;
}

.custom-table-header-last-cell {
  border-right: 1px solid #BABABA;
}

.custom-table-body  {
  display: table-row-group;
  border: 1px solid #BABABA;
}

.custom-table-row {
  display: table-row;
}

.custom-table-row:nth-child(even)  {
  background-color: #f1f1f1;
}

.custom-table-body-cell{
  display: table-cell;
  border-right: 1px solid #BABABA;
  border-bottom: 1px solid #BABABA;
  padding: 4px 8px;
}

.enzyme-details-table-body-cell {
  cursor: pointer;
  border-left: 1px solid #BABABA;
}

.enzyme-details-table-header {
  width: 100%;
}

#enzyme-details-table {
  margin-bottom: 20px;
}

.cut-position-cell {
  width: 15%;
}

.site-flank-cell {
  width: 35%;
}

.methyl-cell {
  width: 10%;
}

.enzyme-details-container{
  max-height: calc(100vh - 130px);
  overflow-y: scroll;
}

.enzyme-details-table {
  border-collapse: separate;
  border-spacing: 0;
  padding-left: 0px;
  padding-right: 0px;
  border-left: 1px solid #BABABA;
  border-top: 0px;
  border-bottom: 0px;
}

.enzyme-details-table th{
  border-right: 0px;
  border-bottom: 1px solid #BABABA;
}

.enzyme-details-table td{
  border-top: 0px !important;
}

.too-many-sites-cell{
  color:  #cf324e;
}

.recognition-site-text{
  color:  #cf324e;
}

.wait {
  display: none;
  position: fixed;
  width: 100%;
  height: 100%;
  top: 0;
  left: 0;
  right: 0;
  bottom: 0;
  z-index: 2;
  padding: 2px;
  align-items: center;
  justify-content: center;
}

#tooltip {
  background: cornsilk;
  border: 1px solid black;
  border-radius: 3px;
  padding: 5px;
}

.checkbox-margin {
  margin-top: 6px !important;
}